YC Biotech

151 companies · 128 active · 48% AI · most in S21 (15)

Halmos LabsRebuilding the drug discovery pipeline around agentsYC F26LundStartup →AI

GamgeeCuring cancer. Starting with dogs.YC S26San FranciscoStartup →Other

GutgutgooseWe sequence your gut and build the probiotics it’s missingYC S26San FranciscoStartup →AI

Illume Labs24/7 Personal Health & Longevity CompanionYC S26San FranciscoStartup →Other

MolagriResistance free pesticides.YC S26TorontoStartup →AI

NeuromorphicBuilding robots to automate wetlabsYC S26San FranciscoStartup →AI

OsseusData research lab for aligned health and biological AIYC S26LondonStartup →AI

RasynMaking chemicals 100,000x fasterYC S26San FranciscoStartup →AI

Spectre IntelligenceWe are a multi-strategy trading firm that trains AI traders.YC S26San FranciscoStartup →AI

WonderTxExtrapolative AI to unlock First-in-Class drugsYC S26San FranciscoStartup →AI

Enjamb LabsThe AI Workforce for BiopharmaYC X26San FranciscoStartup →AI

InferaControl lab instruments with natural language.YC X26San FranciscoStartup →AI

10x ScienceThe AI-native platform for next-generation protein characterization.YC W26San FranciscoStartup →AI

OriginAI and Data for Cancer TherapeuticsYC W26San FranciscoStartup →AI

Anto BiosciencesA Foundation Model for Microbial Communities.YC F25San FranciscoStartup →AI

Paceline BioBiospecimen logistics & operations layer to accelerate drug devYC F25BoulderStartup →AI

ScoopAutomating regulatory submissions for life sciencesYC F25San FranciscoStartup →AI

ConvexiaThe world's first AI-maximalist pharma companyYC S25San FranciscoStartup →AI

PanoptiveAgent systems for clinical development workYC S25San FranciscoStartup →AI

TwentyTwoAI infrastructure for biosecurityYC S25New York CityStartup →AI

BramanteLife sciences reagents and softwareYC X25BostonStartup →AI

FrekilRWE Generation in minutesYC X25San FranciscoStartup →AI

Synthio LabsAgentic AI platform for Pharma GTM teamsYC X25San FranciscoStartup →AI

DelineateAgents for Accelerated Clinical Trial DesignYC W25BostonStartup →AI

RaycasterAgentic AI for knowledge workYC F24New York CityStartup →AI

ReticularScaling Genomic AI for Embryo SelectionYC F24BostonStartup →Other

1849 bioEngineering microbes for miners to unlock billions in trapped metalYC S24San FranciscoStartup →Other

ACXNext-generation biocides for sustainable agriculture at scaleYC S24New York CityStartup →AI

AminoAnalyticaThe AI scientist for always-on biodefenseYC S24LondonStartup →AI

Ångström AIGen AI molecular simulations that reproduce wetlab resultsYC S24San FranciscoStartup →AI

AnthrogenWe work on generalizable tools for the next era of biotech.YC S24San FranciscoStartup →AIInactive

Baseline AIAI document creation and data management for clinical trialsYC S24San FranciscoStartup →Other

BiocartesianConverting biology into digital molecular mapsYC S24PhiladelphiaStartup →AI

Evolvere BioSciencesMaking Next-Generation Antibiotics that Outpace Bacterial EvolutionYC S24OxfordStartup →Other

Kopra BioGenetically engineered viruses that teach your immune system to kill…YC S24San FranciscoStartup →AI

Ligo BiosciencesEnzyme design models.YC S24San FranciscoStartup →AI

UndermindAn AI agent for scientific researchYC S24San FranciscoStartup →Other

Eris BiotechOur drugs engage the immune system to fight tumorsYC W24Salt Lake CityStartup →AI

GloGloCuring and preventing type 1 diabetesYC W24San FranciscoStartup →Other

Granza BioBuilding programmable therapeutics for the immune systemYC W24San FranciscoStartup →Other

ParcelBioElevated mRNA for transformative medicines.YC W24San FranciscoStartup →Other

SynsoryBio"If-then" conditional logic for protein drugsYC W24BostonStartup →AI

Tamarind BioAI Inference Platform for Drug DiscoveryYC W24San FranciscoStartup →Other

Velorum TherapeuticsBreakthrough medicines unlocking the biology of hemeYC W24San FranciscoStartup →AI

GleamRunning clinical trials with AIYC S23San FranciscoStartup →DataInactive

MantleBioTransform scientific data into discoveriesYC S23Startup →AI

Maven BioLive intelligence for biopharma teams.YC S23BostonStartup →AI

NanograbDeliver genes to any cell with AIYC S23LondonStartup →AI

NumenEngineering a future without cancer deaths.YC S23San FranciscoStartup →Other

Ohmic BiosciencesGenetically engineering plants for disease resistance.YC S23San FranciscoStartup →Other

Adventris PharmaceuticalsAdventris makes cancer vaccinesYC W23BaltimoreStartup →AI

Diffuse BioGenerative AI for protein designYC W23San FranciscoStartup →Other

InvitrisCreating new protein-based drugs at scaleYC W23MunichStartup →AIInactive

Lavo Life SciencesAI for drug formulationYC W23Startup →AI

MiracleAccelerate clinical trials with real-time, actionable insightsYC W23San FranciscoStartup →Other

Modulari-TWe teach your immune system to attack and cure cancerYC W23MontrealStartup →AI

Pando BioscienceGen-AI Designed Enzymes for Pharmaceutical InnovationYC W23BostonStartup →Other

ALT TEXBiodegradable and carbon neutral textiles, engineered from food waste.YC S22TorontoStartup →AI

Birch BiosciencesWe recycle plastic using engineered enzymesYC S22PortlandStartup →Other

Cisterna BiologicsHigh quality mRNA for therapeutic applicationYC S22San DiegoStartup →Other

Guardian BioDendritic cell-based platform for cancer therapyYC S22BostonStartup →AI

LaminOpen data platform for traceable, multimodal AIYC S22BYStartup →AI

QuinnYour biopharma team, from molecule design to portfolio strategyYC S22San FranciscoStartup →AI

Serinus BiosciencesCombinations therapy by rational designYC S22New York CityStartup →Other

Signatur BiosciencesSimple tests for complex diseases.YC S22LondonStartup →Other

Alga BiosciencesWe stop cows from burping methane.YC W22San FranciscoStartup →Other

AlixiaTargeting the Tumor Ecosystem to address cancer drug resistance.YC W22San FranciscoStartup →Other

Andson BiotechEmpowering Mass Spec for Biotech and BeyondYC W22AtlantaStartup →AI

Brown FoodsMaking 'REAL' Cow and Human Milk!YC W22BostonStartup →OtherAcquired

Engage BioPotent, durable, and redosable non-viral genetic medicinesYC W22San FranciscoStartup →AIAcquired

HypaHubA Cloud-Based Bioinformatics and AI PlatformYC W22San FranciscoStartup →AI

InvertData analytics software for biomanufacturing.YC W22San FranciscoStartup →Other

Origami Therapeutics, Inc.Oral drugs to halt neurodegenerationYC W22San DiegoStartup →AI

Rosebud BiosciencesGrowing micro-organs to find new drugsYC W22San FranciscoStartup →Other

Torpedo TherapeuticsHigh-precision, closed-loop neuromodulation devicesYC W22BostonStartup →Other

BLUUMBIOWe make bacteria and plants that clean up pollution.YC S21San FranciscoStartup →Other

Catena BiosciencesUsing protein coupling to build new therapiesYC S21San FranciscoStartup →Other

EpinomaWe engineer proteins that control the operating system of biology.YC S21San FranciscoStartup →AI

Harmonic DiscoveryMulti-targeted therapeutics to treat complex diseasesYC S21New York CityStartup →Other

Kiwi BiosciencesPatent-pending enzymes to break down common dietary triggersYC S21BostonStartup →AI

Medium BiosciencesAI-designed Affinity ReagentsYC S21AustinStartup →OtherInactive

Micro MeatTechnologies for scaling up cultured/clean meat productionYC S21MonterreyStartup →AI

Mindstate Design LabsProgrammable biology company for psychoactive effect designYC S21San FranciscoStartup →AI

Output LabsThe foundation for the next era of scienceYC S21New York CityStartup →AI

Parallel BioUsing the immune system to cure diseaseYC S21San FranciscoStartup →Other

Pirouette PharmaWe make injections as easy as pushing a button!YC S21BostonStartup →Other

Sensible BiotechnologiesUnlocking the next generation of mRNA medicinesYC S21OxfordStartup →AI

SFA TherapeuticsRegulating the immune system to block cancer & autoimmune diseasesYC S21PhiladelphiaStartup →Other

Talus BioDiscovering drugs that target the DNA regulomeYC S21SeattleStartup →Other

Yemaachi BiotechnologyDiversifying precision cancer diagnostics and treatmentsYC S21AccraStartup →Other

Entelexo BiotherapeuticsCreating a New Class of Drugs to Address Incurable Autoimmune DiseasesYC W21IrvineStartup →Other

Reshape BiotechRobots that automate the everyday tasks of microbiologists.YC W21CopenhagenStartup →Other

Serna BioGenetic Medicine with Small MoleculesYC W21San FranciscoStartup →Other

Trestle BiotherapeuticsBioengineered kidneys for patients with kidney failureYC W21San DiegoStartup →Other

Valink TherapeuticsDiscovering bispecific antibody drug-conjugates (BsADC) against cancerYC W21BostonStartup →Other

Future FieldsWe make unmakeable proteins with radical advanced biomanufacturing.YC S20EdmontonStartup →AI

Kernal BiologicsKernal is creating mRNA 2.0 therapies that work in specific cellsYC S20BostonStartup →AI

NephrogenCurative genetic medicines for kidney diseasesYC S20New York CityStartup →OtherPublicPardes BiosciencesWe break virusesYC S20San FranciscoStartup →AI

Algen BiotechnologiesUsing CRISPR to find treatments for cancer and inflammationYC W20San FranciscoStartup →

Company	Category	Status	Program
Halmos LabsRebuilding the drug discovery pipeline around agentsteam of 3YC F26ActiveAI	AI	Active	YCF26
GamgeeCuring cancer. Starting with dogs.team of 2YC S26ActiveAI	AI	Active	YCS26
GutgutgooseWe sequence your gut and build the probiotics it’s missingteam of 7YC S26ActiveOther	Other	Active	YCS26
Illume Labs24/7 Personal Health & Longevity Companionteam of 3YC S26ActiveAI	AI	Active	YCS26
MolagriResistance free pesticides.team of 4hiringYC S26ActiveOther	Other	Active	YCS26
NeuromorphicBuilding robots to automate wetlabsteam of 3YC S26ActiveAI	AI	Active	YCS26
OsseusData research lab for aligned health and biological AIteam of 2YC S26ActiveAI, Data	AI, Data	Active	YCS26
RasynMaking chemicals 100,000x fasterteam of 3YC S26ActiveAI	AI	Active	YCS26
Spectre IntelligenceWe are a multi-strategy trading firm that trains AI traders.team of 2YC S26ActiveAI	AI	Active	YCS26
WonderTxExtrapolative AI to unlock First-in-Class drugsteam of 3YC S26ActiveAI	AI	Active	YCS26
Enjamb LabsThe AI Workforce for Biopharmateam of 2YC X26ActiveAI	AI	Active	YCX26
InferaControl lab instruments with natural language.team of 2hiringYC X26ActiveAI	AI	Active	YCX26
10x ScienceThe AI-native platform for next-generation protein characterization.team of 5hiringYC W26ActiveAI	AI	Active	YCW26
OriginAI and Data for Cancer Therapeuticsteam of 8hiringYC W26ActiveAI	AI	Active	YCW26
Anto BiosciencesA Foundation Model for Microbial Communities.team of 4YC F25ActiveAI	AI	Active	YCF25
Paceline BioBiospecimen logistics & operations layer to accelerate drug devteam of 3YC F25ActiveAI	AI	Active	YCF25
ScoopAutomating regulatory submissions for life sciencesteam of 2YC F25ActiveAI	AI	Active	YCF25
ConvexiaThe world's first AI-maximalist pharma companyteam of 4YC S25ActiveAI	AI	Active	YCS25
PanoptiveAgent systems for clinical development workteam of 2YC S25ActiveAI, Devtools	AI, Devtools	Active	YCS25
TwentyTwoAI infrastructure for biosecurityteam of 3YC S25ActiveAI	AI	Active	YCS25
BramanteLife sciences reagents and softwareteam of 2YC X25ActiveAI	AI	Active	YCX25
FrekilRWE Generation in minutesteam of 2YC X25ActiveAI	AI	Active	YCX25
Synthio LabsAgentic AI platform for Pharma GTM teamsteam of 29hiringYC X25ActiveAI	AI	Active	YCX25
DelineateAgents for Accelerated Clinical Trial Designteam of 20YC W25ActiveAI, Devtools	AI, Devtools	Active	YCW25
RaycasterAgentic AI for knowledge workteam of 6hiringYC F24ActiveAI, Data	AI, Data	Active	YCF24
ReticularScaling Genomic AI for Embryo Selectionteam of 2YC F24ActiveAI	AI	Active	YCF24
1849 bioEngineering microbes for miners to unlock billions in trapped metalteam of 3YC S24ActiveOther	Other	Active	YCS24
ACXNext-generation biocides for sustainable agriculture at scaleteam of 4YC S24ActiveOther	Other	Active	YCS24
AminoAnalyticaThe AI scientist for always-on biodefenseteam of 3YC S24ActiveAI	AI	Active	YCS24
Ångström AIGen AI molecular simulations that reproduce wetlab resultsteam of 5YC S24ActiveAI	AI	Active	YCS24
AnthrogenWe work on generalizable tools for the next era of biotech.team of 15hiringYC S24ActiveAI	AI	Active	YCS24
Baseline AIAI document creation and data management for clinical trialsteam of 2YC S24InactiveAI	AI	Inactive	YCS24
BiocartesianConverting biology into digital molecular mapsteam of 2YC S24ActiveOther	Other	Active	YCS24
Evolvere BioSciencesMaking Next-Generation Antibiotics that Outpace Bacterial Evolutionteam of 3YC S24ActiveAI	AI	Active	YCS24
Kopra BioGenetically engineered viruses that teach your immune system to kill…team of 2YC S24ActiveOther	Other	Active	YCS24
Ligo BiosciencesEnzyme design models.team of 4YC S24ActiveAI	AI	Active	YCS24
UndermindAn AI agent for scientific researchYC S24ActiveAI, Data	AI, Data	Active	YCS24
Eris BiotechOur drugs engage the immune system to fight tumorsteam of 2YC W24ActiveOther	Other	Active	YCW24
GloGloCuring and preventing type 1 diabetesteam of 3hiringYC W24ActiveAI	AI	Active	YCW24
Granza BioBuilding programmable therapeutics for the immune systemteam of 8YC W24ActiveOther	Other	Active	YCW24
ParcelBioElevated mRNA for transformative medicines.team of 6YC W24ActiveOther	Other	Active	YCW24
SynsoryBio"If-then" conditional logic for protein drugsteam of 2YC W24ActiveOther	Other	Active	YCW24
Tamarind BioAI Inference Platform for Drug Discoveryteam of 20hiringYC W24ActiveAI	AI	Active	YCW24
Velorum TherapeuticsBreakthrough medicines unlocking the biology of hemeteam of 5YC W24ActiveOther	Other	Active	YCW24
GleamRunning clinical trials with AIteam of 4YC S23ActiveAI	AI	Active	YCS23
MantleBioTransform scientific data into discoveriesteam of 7YC S23InactiveData	Data	Inactive	YCS23
Maven BioLive intelligence for biopharma teams.team of 10hiringYC S23ActiveAI	AI	Active	YCS23
NanograbDeliver genes to any cell with AIteam of 5YC S23ActiveAI	AI	Active	YCS23
NumenEngineering a future without cancer deaths.team of 18hiringYC S23ActiveAI	AI	Active	YCS23
Ohmic BiosciencesGenetically engineering plants for disease resistance.team of 2YC S23ActiveOther	Other	Active	YCS23
Adventris PharmaceuticalsAdventris makes cancer vaccinesteam of 7YC W23ActiveOther	Other	Active	YCW23
Diffuse BioGenerative AI for protein designteam of 10hiringYC W23ActiveAI	AI	Active	YCW23
InvitrisCreating new protein-based drugs at scaleteam of 6YC W23ActiveOther	Other	Active	YCW23
Lavo Life SciencesAI for drug formulationteam of 3YC W23InactiveAI	AI	Inactive	YCW23
MiracleAccelerate clinical trials with real-time, actionable insightsteam of 7YC W23ActiveAI	AI	Active	YCW23
Modulari-TWe teach your immune system to attack and cure cancerteam of 4YC W23ActiveOther	Other	Active	YCW23
Pando BioscienceGen-AI Designed Enzymes for Pharmaceutical Innovationteam of 5YC W23ActiveAI	AI	Active	YCW23
ALT TEXBiodegradable and carbon neutral textiles, engineered from food waste.team of 10YC S22ActiveOther	Other	Active	YCS22
Birch BiosciencesWe recycle plastic using engineered enzymesteam of 10YC S22ActiveAI	AI	Active	YCS22
Cisterna BiologicsHigh quality mRNA for therapeutic applicationteam of 2YC S22ActiveOther	Other	Active	YCS22
Guardian BioDendritic cell-based platform for cancer therapyteam of 2YC S22ActiveOther	Other	Active	YCS22
LaminOpen data platform for traceable, multimodal AIteam of 12YC S22ActiveAI, Data, Devtools	AI, Data, Devtools	Active	YCS22
QuinnYour biopharma team, from molecule design to portfolio strategyteam of 5YC S22ActiveAI	AI	Active	YCS22
Serinus BiosciencesCombinations therapy by rational designteam of 6YC S22ActiveAI	AI	Active	YCS22
Signatur BiosciencesSimple tests for complex diseases.team of 5YC S22ActiveOther	Other	Active	YCS22
Alga BiosciencesWe stop cows from burping methane.team of 6YC W22ActiveOther	Other	Active	YCW22
AlixiaTargeting the Tumor Ecosystem to address cancer drug resistance.team of 2YC W22ActiveOther	Other	Active	YCW22
Andson BiotechEmpowering Mass Spec for Biotech and Beyondteam of 12YC W22ActiveOther	Other	Active	YCW22
Brown FoodsMaking 'REAL' Cow and Human Milk!team of 5YC W22ActiveAI	AI	Active	YCW22
Engage BioPotent, durable, and redosable non-viral genetic medicinesteam of 10acquiredYC W22AcquiredOther	Other	Acquired	YCW22
HypaHubA Cloud-Based Bioinformatics and AI Platformteam of 6acquiredYC W22AcquiredAI, Data	AI, Data	Acquired	YCW22
InvertData analytics software for biomanufacturing.team of 25hiringYC W22ActiveAI	AI	Active	YCW22
Origami Therapeutics, Inc.Oral drugs to halt neurodegenerationteam of 4YC W22ActiveOther	Other	Active	YCW22
Rosebud BiosciencesGrowing micro-organs to find new drugsteam of 3YC W22ActiveAI	AI	Active	YCW22
Torpedo TherapeuticsHigh-precision, closed-loop neuromodulation devicesteam of 5YC W22ActiveOther	Other	Active	YCW22
BLUUMBIOWe make bacteria and plants that clean up pollution.team of 42 programsYC S21 +1ActiveOther	Other	Active	YC +1S21
Catena BiosciencesUsing protein coupling to build new therapiesteam of 7YC S21ActiveOther	Other	Active	YCS21
EpinomaWe engineer proteins that control the operating system of biology.team of 8hiringYC S21ActiveOther	Other	Active	YCS21
Harmonic DiscoveryMulti-targeted therapeutics to treat complex diseasesteam of 8YC S21ActiveAI	AI	Active	YCS21
Kiwi BiosciencesPatent-pending enzymes to break down common dietary triggersteam of 10YC S21ActiveOther	Other	Active	YCS21
Medium BiosciencesAI-designed Affinity Reagentsteam of 6YC S21ActiveAI	AI	Active	YCS21
Micro MeatTechnologies for scaling up cultured/clean meat productionYC S21InactiveOther	Other	Inactive	YCS21
Mindstate Design LabsProgrammable biology company for psychoactive effect designteam of 7YC S21ActiveAI	AI	Active	YCS21
Output LabsThe foundation for the next era of scienceteam of 10hiringYC S21ActiveAI	AI	Active	YCS21
Parallel BioUsing the immune system to cure diseaseteam of 20hiringYC S21ActiveAI	AI	Active	YCS21
Pirouette PharmaWe make injections as easy as pushing a button!team of 9hiringYC S21ActiveOther	Other	Active	YCS21
Sensible BiotechnologiesUnlocking the next generation of mRNA medicinesteam of 55YC S21ActiveOther	Other	Active	YCS21
SFA TherapeuticsRegulating the immune system to block cancer & autoimmune diseasesteam of 4YC S21ActiveAI	AI	Active	YCS21
Talus BioDiscovering drugs that target the DNA regulometeam of 16YC S21ActiveOther	Other	Active	YCS21
Yemaachi BiotechnologyDiversifying precision cancer diagnostics and treatmentsteam of 16YC S21ActiveOther	Other	Active	YCS21
Entelexo BiotherapeuticsCreating a New Class of Drugs to Address Incurable Autoimmune Diseasesteam of 3YC W21ActiveOther	Other	Active	YCW21
Reshape BiotechRobots that automate the everyday tasks of microbiologists.team of 40YC W21ActiveOther	Other	Active	YCW21
Serna BioGenetic Medicine with Small Moleculesteam of 5YC W21ActiveOther	Other	Active	YCW21
Trestle BiotherapeuticsBioengineered kidneys for patients with kidney failureteam of 2YC W21ActiveOther	Other	Active	YCW21
Valink TherapeuticsDiscovering bispecific antibody drug-conjugates (BsADC) against cancerteam of 15YC W21ActiveOther	Other	Active	YCW21
Future FieldsWe make unmakeable proteins with radical advanced biomanufacturing.team of 34YC S20ActiveOther	Other	Active	YCS20
Kernal BiologicsKernal is creating mRNA 2.0 therapies that work in specific cellsteam of 20YC S20ActiveAI	AI	Active	YCS20
NephrogenCurative genetic medicines for kidney diseasesteam of 5YC S20ActiveAI	AI	Active	YCS20
Pardes BiosciencesWe break virusespublicteam of 2YC S20PublicOther	Other	Public	YCS20
Algen BiotechnologiesUsing CRISPR to find treatments for cancer and inflammationteam of 17YC W20ActiveAI	AI	Active	YCW20

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