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14,448 startups · 29 programs

Serna Bio

Active · Genetic Medicine with Small Molecules

WebsiteYC profile

Why it ranks

How the rank works
8signal of 100 · rising 2
  • team of 5Team size · YC's directory+4
  • went through YCProgram · this site+4

A sum of public facts, not a judgement and not investment advice.

Competitors

OtherAcquiredEngage BioShared: genetic medicine, drug discovery, biotechYC W22San FranciscoStartup →AINephrogenShared: genetic medicine, biotech, diseaseYC S20New York CityStartup →OtherOrigami Therapeutics, Inc.Shared: small molecule, drug discovery, biotechYC W22San DiegoStartup →OtherEris BiotechShared: small molecule, drug discovery, biotechYC W24Salt Lake CityStartup →OtherNuntius TherapeuticsShared: genetic medicine, therapeuticsYC W21LondonStartup →
Companies closest to Serna Bio
Company
Engage BioShared: genetic medicine, drug discovery, biotechYC W22AcquiredOther
NephrogenShared: genetic medicine, biotech, diseaseYC S20ActiveAI
Origami Therapeutics, Inc.Shared: small molecule, drug discovery, biotechYC W22ActiveOther
Eris BiotechShared: small molecule, drug discovery, biotechYC W24ActiveOther
Nuntius TherapeuticsShared: genetic medicine, therapeuticsYC W21ActiveOther

Adjacent

AIChemT BiotechnologyShared: small moleculeMassChallenge Switzerland and UK 2026SingaporeStartup →AIAltay TherapeuticsShared: small molecule, drug discovery, biotechYC W20San FranciscoStartup →OtherInactiveEncepheal TherapeuticsShared: small molecule, drug discovery, treatYC S19Winston-SalemStartup →OtherVelorum TherapeuticsShared: drug discovery, biotech, medicineYC W24San FranciscoStartup →AIAlgen BiotechnologiesShared: modulate rna, drug discovery, biotechYC W20San FranciscoStartup →
Companies next to Serna Bio
Company
ChemT BiotechnologyShared: small moleculeMassChallenge Switzerland and UK 2026Not statedAI
Altay TherapeuticsShared: small molecule, drug discovery, biotechYC W20ActiveAI
Encepheal TherapeuticsShared: small molecule, drug discovery, treatYC S19InactiveOther
Velorum TherapeuticsShared: drug discovery, biotech, medicineYC W24ActiveOther
Algen BiotechnologiesShared: modulate rna, drug discovery, biotechYC W20ActiveAI

Also from W21

All of W21
AIAbacumThe AI-native FP&A platform that helps Finance teams drive business…YC W21New York CityStartup →AIAlineaAutomated investing for the next generation 💸YC W21New York CityStartup →Developer toolsAlokaiFrontend Platform for eCommerceYC W21WarsawStartup →AIAnimaThe next generation care enablement platformYC W21LondonStartup →AIarnataAI workers for the logistics industry.YC W21San FranciscoStartup →Developer toolsArpioRecover from any outage in 10 minutes or less.YC W21DurhamStartup →
Company
AbacumThe AI-native FP&A platform that helps Finance teams drive business…team of 125hiringActiveAI
AlineaAutomated investing for the next generation 💸team of 12hiringActiveAI
AlokaiFrontend Platform for eCommerceteam of 100ActiveDevtools
AnimaThe next generation care enablement platformteam of 20hiringActiveAI
arnataAI workers for the logistics industry.team of 15hiringActiveAI
ArpioRecover from any outage in 10 minutes or less.team of 7ActiveDevtools

About Serna Bio

Serna Bio is developing small molecules to modulate RNA function, unlocking the potential to treat diseases driven by biology intractable by other modalities.

YC batch
W21 · Winter 2021
Status, per YC
Active
Category
Other
Team size
5
Location
San Francisco, CA, USA
Checked
10h ago

YC tags: Biotech, Drug discovery

Changes seen

HeadquartersOct 8, 2026

Moved its headquarters from Ontario, CA, USA; Remote to San Francisco, CA, USA.

Source ↗
RegionsOct 8, 2026

Now lists the region Partly Remote; no longer lists Fully Remote.

Source ↗

Serna Bio in W21: 336 companies, 30% AI

Serna Bio: questions

Which YC batch was Serna Bio in?

Serna Bio was in Y Combinator's Winter 2021 batch (W21).

Is Serna Bio still active?

Y Combinator lists Serna Bio as active.

Where is Serna Bio based?

Serna Bio lists San Francisco, CA, USA as its location on YC's directory.