Cisterna Biologics
YC S22 · Active · High quality mRNA for therapeutic application
Competitors
| Company | Category | Status | Program |
|---|---|---|---|
 Sensible BiotechnologiesShared: synthetic biology, therapeutics, biotechActiveOther | Other | Active | YCS21 |
 ParcelBioShared: synthetic biology, therapeutics, biotechActiveOther | Other | Active | YCW24 |
 Birch BiosciencesShared: molecular scissors, high quality, synthetic biologyActiveAI | AI | Active | YCS22 |
 SynsoryBioShared: synthetic biology, therapeutics, biotechActiveOther | Other | Active | YCW24 |
 Living CarbonShared: high quality, synthetic biology, biotechActiveOther | Other | Active | YCW20 |
Adjacent
| Company | Category | Status | Program |
|---|---|---|---|
 Granza BioShared: synthetic biology, therapeutics, biotechActiveOther | Other | Active | YCW24 |
 Gerostate AlphaShared: therapeutics, biotechInactiveOther | Other | Inactive | YCS18 |
 Helix NanotechnologiesShared: biotech, mrna, solveActiveAI | AI | Active | YCW17 |
 Dorian TherapeuticsShared: therapeutics, biotechAcquiredOther | Other | Acquired | YCS18 |
 Andson BiotechShared: therapeutics, biotech, qualityActiveOther | Other | Active | YCW22 |
Also from S22
All of S22
About Cisterna Biologics
Founded in 2022 and based in San Diego, California, Cisterna Biologics is a technology company. It aims to solve some of the challenges currently facing the biotech industry to develop mRNA-based therapeutics – quality, quantity, longevity and cost of mRNA. As mRNA technology matures, it becomes imperative that these issues are solved so we can fully explore mRNA's endless possibilities as a therapeutic. Cisterna uses proprietary technologies to either remove a contaminant at its source or replace the source itself. For example, to remove double-stranded RNA (dsRNA), we use ribozymes - molecular scissors - to precisely cut the mRNA at its 3’ end. This assures not only 3’ homogeneity, but also eliminates dsRNA, which are primarily produced due to self-templated additions at the 3’ end. Utilizing a PCR-like system to amplify the DNA template in large quantities eliminates the requirement for plasmid enrichment in bacteria, the prime source of endotoxin contamination. These are just a few examples of Cisterna’s powerful technologies being used to achieve our goal of 10x higher quality mRNA for therapeutic application.
- YC batch
- S22 · Summer 2022
- Status, per YC
- Active
- Category
- Other
- Team size
- 2
- Location
- San Diego, CA, USA
- Checked
- 36m ago
YC tags: Synthetic Biology, Biotech, Therapeutics
Cisterna Biologics: questions
Which YC batch was Cisterna Biologics in?
Cisterna Biologics was in Y Combinator's Summer 2022 batch (S22).
Is Cisterna Biologics still active?
Y Combinator lists Cisterna Biologics as active.
Where is Cisterna Biologics based?
Cisterna Biologics lists San Diego, CA, USA as its location on YC's directory.
Sources: each program's public company list, read twice a week. Not affiliated with Y Combinator or any other program. Logos via logo.dev; trademarks belong to their owners.