Sift Biosciences
Plug and Play · Supercharging existing cancer therapies.
Competitors
| Company | Category | Status | Program |
|---|---|---|---|
 Guardian BioShared: cancer therapy, cell, tumorActiveOther | Other | Active | YCS22 |
 Grannus TherapeuticsShared: solid tumor, cancer, novelNot statedOther | Other | Not stated | Plug and Play |
Adjacent
| Company | Category | Status | Program |
|---|---|---|---|
 Reverie LabsShared: cancer therapyAcquiredAI | AI | Acquired | SPC2018 |
 Reverie LabsShared: cancer therapyInactiveAI | AI | Inactive | YCW18 |
 Eris BiotechShared: solid tumor, cancer, developingActiveOther | Other | Active | YCW24 |
 Diapin TherapeuticsShared: critical unmet, therapy, novelNot statedOther | Other | Not stated | Plug and Play |
 GeniPhysShared: novel approach, immunogenic, therapyNot statedOther | Other | Not stated | Plug and Play |
Also from Plug and Play
All of Plug and Play
Programs
| Program | Cohort | Source |
|---|---|---|
 Plug and Play | Not stated | Plug and Play Page |
About Sift Biosciences
Sift is developing first- and best-in-class T-cell modulators that address a critical unmet need in oncology: most solid tumors lack immunogenic targets and remain resistant to current immunotherapies. Sift differentiates by leveraging molecular mimicry—shared genomic sequences between microbes and humans—to design highly immunogenic cancer antigen variants derived from microorganisms. This novel approach activates an otherwise untapped repertoire of pre-existing memory T-cells originally trained against microbial infections. These microbe-reactive T-cells exhibit more robust functionality compared to conventional cancer-specific T-cells. Building upon our oncology proof-of-concept, Sift is also exploring platform applications to selectively expand target-specific regulatory T cells, with the potential to restore immune tolerance in autoimmune diseases. This dual applicability further highlights the transformative potential of our mimicry-based antigen engineering approach.
- Category
- Other
- Location
- United States
- Checked
- 1h ago
Sift Biosciences: questions
Which accelerators did Sift Biosciences go through?
Sift Biosciences is listed by Plug and Play.
Where is Sift Biosciences based?
Sift Biosciences lists United States as its location on Plug and Play's page.
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