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14,448 startups · 29 programs

Nucleo

Active · The first Agentic platform for Oncology

WebsiteYC profile

Why it ranks

How the rank works
9signal of 100 · rising 7
  • went through YCProgram · this site+4
  • team of 2Team size · YC's directory+2.5
  • hiringHiring · Titles (titles.fru.dev), YC+2

A sum of public facts, not a judgement and not investment advice.

Competitors

AISingularity.AIShared: extract insight, healthPlug and PlayUnited StatesStartup →
Companies closest to Nucleo
Company
Singularity.AIShared: extract insight, healthPlug and Play Not statedAI

Adjacent

OtherPaperLabShared: extract insightAntler 2024AustraliaStartup →AISpiraldot Health Inc.Shared: oncology, supportAntler 2024USStartup →AIAcquiredScopeAIShared: extract insight, supportYC W17Los AngelesStartup →AIRadicalShared: oncologyEF 2024LondonStartup →OtherT-ICU Co., Ltd.Shared: hospital, treatment, supportPlug and PlayJapanStartup →
Companies next to Nucleo
Company
PaperLabShared: extract insightAntler 2024Not statedOther
Spiraldot Health Inc.Shared: oncology, supportAntler 2024Not statedAI
ScopeAIShared: extract insight, supportYC W17AcquiredAI
RadicalShared: oncologyEF 2024Not statedAI
T-ICU Co., Ltd.Shared: hospital, treatment, supportPlug and Play Not statedOther

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AmikaTurn any spare computer into agent devboxes or CI runnersteam of 2ActiveAI, Devtools

Founders

  • Angelica IacovelliFounder/CEO
  • Luca PegolottiFounder/CTO

About Nucleo

We help oncologists and radiologists extract insights from CT scans to support tumor characterization and treatment. The hospitals we work with include Stanford Hospital, Cedars-Sinai, UCI Health, and Weill Cornell.

YC batch
F25 · Fall 2025
Status, per YC
Active
Category
AI
Team size
2
Location
San Francisco, CA, USA
Founded
2025
Checked
13h ago

Changes seen

HiringNov 5, 2026

Started hiring.

Source ↗

Nucleo in F25: 146 companies, 88% AI

LinkedIn

Nucleo: questions

Which YC batch was Nucleo in?

Nucleo was in Y Combinator's Fall 2025 batch (F25).

Is Nucleo still active?

Y Combinator lists Nucleo as active.

Who founded Nucleo?

Nucleo's founders, as listed on its YC page: Angelica Iacovelli (Founder/CEO), Luca Pegolotti (Founder/CTO).

Where is Nucleo based?

Nucleo lists San Francisco, CA, USA as its location on YC's directory.